Fig. 1 · Structure
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JAMM protein inhibitor 2
JAMM Protease Inhibitor
JAMM Protein Inhibitor 2 is a selective inhibitor targeting JAMM proteases, exhibiting IC50 values of 10 μM for thrombin, 46 μM for Rpn11, and 89 μM for MMP2. This compound demonstrates significant biological activity relevant to cancer research, particularly in elucidating mechanisms involving proteolysis and signaling pathways. Researchers can utilize JAMM Protein Inhibitor 2 to explore potential therapeutic strategies against cancer and investigate the role of JAMM proteases in various pathophysiological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 848249-35-4 |
| Applications | JAMM Protease Inhibitor |
| Formula | C21H26N2O2 |
| Molecular Weight | 338.44 |
| SMILES | O=C(NC1=CC=C(N2CCCC2)C=C1C)COC3=CC=CC=C3CC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.