Fig. 1 · Structure
Documents & Downloads
JAS239
ChoK Inhibitor
JAS239 is a potent ChoK inhibitor that effectively crosses the blood-brain barrier. By inhibiting phosphocholine synthesis, JAS239 leads to the decreased expression of E2F1 protein, which is crucial in cell cycle regulation. This compound demonstrates noteworthy anti-tumor activity against glioblastoma and possesses near-infrared fluorescence properties, making it a valuable tool for research in glioblastoma and related fields.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1630288-74-2 |
| Applications | ChoK Inhibitor |
| Formula | C31H37ClN2O2 |
| Molecular Weight | 505.10 |
| SMILES | [Cl-].OCCN1C=2C=CC=CC2C(C1=CC=CC=CC=CC3=[N+](C=4C=CC=CC4C3(C)C)CCO)(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.