Fig. 1 · Structure
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Jasplakinolide
Actin Polymerization Inducer
Jasplakinolide is a potent actin polymerization inducer that stabilizes pre-existing actin filaments by binding competitively to F-actin, with a Kd of 15 nM. Derived from marine sponges, this naturally occurring cyclic peptide exhibits both fungicidal and anti-cancer properties. Its primary applications include the study of cytoskeletal dynamics and the investigation of cellular processes related to actin regulation in various biological systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inducer |
| CAS Number | 102396-24-7 |
| Applications | Actin Polymerization Inducer |
| Formula | C36H45BrN4O6 |
| Molecular Weight | 709.67 |
| SMILES | BrC1=C(C2=CC=CC=C2N1)C[C@@H](N(C([C@@H](NC([C@H](C/C(C)=C/[C@@H]3C)C)=O)C)=O)C)C(N[C@](C(C=C4)=CC=C4O)([H])CC(O[C@H](C3)C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.