Fig. 1 · Structure
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JB002
Myosin II Inhibitor
JB002 is a selective inhibitor of myosin II, exhibiting an IC50 of ≤10 μM. This compound is significant for studying various conditions such as muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy. JB002 aids in understanding the role of myosin II in muscle dynamics and associated pathological states, providing a valuable tool for biomedical research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 30408-07-2 |
| Applications | Myosin II Inhibitor |
| Formula | C18H15NO3 |
| Molecular Weight | 293.32 |
| SMILES | C/C(C1=C(C2=CC=CC=C2OC1=O)O)=N\CC3=CC=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.