Fig. 1 · Structure
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JC-229
TbRPA1 Inhibitor
JC-229 is a selective inhibitor of the TbRPA1 protein, effectively targeting RPA1 in Trypanosoma brucei. This compound demonstrates significant potential in the study of Human African Trypanosomiasis (HAT), allowing for investigations into the parasite's replication and survival mechanisms. Its application in research may contribute to the development of innovative therapeutic strategies against this infectious disease.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3026716-22-0 |
| Applications | TbRPA1 Inhibitor |
| Formula | C20H14Cl4N2O3S |
| Molecular Weight | 504.21 |
| SMILES | O=C(NC1=CC=C(Cl)C(Cl)=C1)C2=CC=C(C)C(S(=O)(NC3=CC=C(Cl)C(Cl)=C3)=O)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.