Fig. 1 · Structure
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JCC76
Antitumor Agent
JCC76 is a derivative of Nimesulide that targets antitumor activity. It effectively inhibits the proliferation of Her2-positive breast cancer cells, specifically the SKBR-3 cell line, with an IC50 value of 3.43 μM. This compound is relevant for research applications focused on developing targeted therapies for breast cancer and studying the mechanisms of action of anti-cancer agents.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1021926-22-6 |
| Applications | Antitumor Agent |
| Formula | C24H32N2O4S |
| Molecular Weight | 444.59 |
| SMILES | O=C(C1CCCCC1)NC2=CC=C(N(S(=O)(C)=O)C)C(OCC3=CC(C)=CC=C3C)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.