Catalog No.: A20837

CB1R antagonist


JD-5037 Chemical Structure

CAS NO. 1392116-14-1

JD-5037 is a novel, peripherally restricted CB1R antagonist with an IC50 of 1.5 nM.

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Biological Activity

JD-5037 is a novel, peripherally restricted CB1R antagonist with an IC50 of 1.5 nM.
In vitro DMSO 90 mg/mL (157.19 mM)
Water Insoluble
Ethanol 2 mg/mL (3.49 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.47 mL 87.33 mL 174.67 mL
0.5 mM 3.49 mL 17.47 mL 34.93 mL
1 mM 1.75 mL 8.73 mL 17.47 mL
5 mM 0.35 mL 1.75 mL 3.49 mL

*The above data is based on the productmolecular weight 572.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20837
Actions Antagonist
CAS No. 1392116-14-1
Formula C27H27Cl2N5O3S
M. Wt 572.51
Purity >98%
Synonyms JD5037, JD 5037
SMILES NC([[email protected]](C(C)C)/N=C(NS(=O)(C1=CC=C(Cl)C=C1)=O)\N2N=C(C3=CC=C(Cl)C=C3)[[email protected]@H](C4=CC=CC=C4)C2)=O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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