JH-II-127

Name: JH-II-127
Brand: Adooq Bioscience
SKU: A15777
Rating: 5 (288 reviews)

Catalog No.: A15777

LRRK2 inhibitor

JH-II-127 is a highly potent, selective, and brain penetrant LRRK2 inhibitor, with IC50 of 6.6 nM, 2.2 nM ,47.7 nM for LRRK2-wild-type, LRRK2-G2019S, LRRK2-A2016T.

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Grouped product items
Size	Price	Stock
1mg	$40.00	In stock
5mg	$100.00	In stock
10mg	$165.00	In stock
25mg	$290.00	In stock
50mg	$470.00	In stock
100mg	$670.00	In stock
*10mM 1mL in DMSO**	$110.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	JH-II-127 is a highly potent, selective, and brain penetrant LRRK2 inhibitor, with IC50 of 6.6 nM, 2.2 nM ,47.7 nM for LRRK2-wild-type, LRRK2-G2019S, LRRK2-A2016T.

Product Information

Catalog Num	A15777
Formula	C19H21ClN6O3
Molecular Weight	416.86
CAS Number	1700693-08-8
SMILES	CNC1=NC(=NC2=C1C(=CN2)Cl)NC3=C(C=C(C=C3)C(=O)N4CCOCC4)OC
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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