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LRRK2 inhibitor

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Catalog No. A15777

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
JH-II-127 5mg A15777-5

Regular Price: $120.00

Special Price: $108.00

JH-II-127 10mg A15777-10

Regular Price: $200.00

Special Price: $180.00

JH-II-127 25mg A15777-25

Regular Price: $400.00

Special Price: $360.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

JH-II-127 is a highly potent, selective, and brain penetrant LRRK2 inhibitor, with IC50 of 6.6 nM, 2.2 nM ,47.7 nM for LRRK2-wild-type, LRRK2-G2019S, LRRK2-A2016T.


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Chemical Information

Catalog Num A15777
Actions Inhibitor
M. Wt 416.86
Formula C19H21ClN6O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1700693-08-8
Synonyms N/A

Biological Activity

JH-II-127 is a highly potent, selective, and brain penetrant LRRK2 inhibitor, with IC50 of 6.6 nM, 2.2 nM ,47.7 nM for LRRK2-wild-type, LRRK2-G2019S, LRRK2-A2016T.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.99 mL 119.94 mL 239.89mL
0.5 mM 4.8 mL 23.99 mL 47.98 mL
1 mM 2.4 mL 11.99 mL 23.99 mL
5 mM 0.48 mL 2.4 mL 4.8 mL

*The above data is based on the productmolecular weight 416.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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