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JH-XI-10-02

Catalog No.: A19556
CDK8 degrader
JH-XI-10-02 is a potent and selective degrader of CDK8, with an IC50 of 159 nM, based on PROTAC.
JH-XI-10-02
Grouped product items
Product Name Price Stock Qty
JH-XI-10-02 1mg
$482.00
In stock
JH-XI-10-02 5mg
$1,445.00
In stock
JH-XI-10-02 10mg
$2,461.00
In stock
JH-XI-10-02 50mg
$7,383.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription JH-XI-10-02 is a potent and selective degrader of CDK8, with an IC50 of 159 nM, based on PROTAC.
Targets
Target Value
Product Information
Catalog Num A19556
Formula C53H69N5O9
Molecular Weight 920.14
CAS Number 2209085-22-1
SMILES O=C(N([C@H]1CC[C@]2(C)C3CC[C@]4(C)[C@@H](C5=CC6=C(C=C5)C=CN=C6)CC[C@@]4([H])[C@]3([H])CCC2C1)C)CCOCCOCCOCCOCCNC7=CC=CC(C(N8C(CC9)C(NC9=O)=O)=O)=C7C8=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Cell Cycle > CDK
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