JH-XVII-10

Name: JH-XVII-10
Brand: Adooq Bioscience
SKU: A31914
Rating: 5 (288 reviews)

Catalog No.: A31914

DYRK1A/DYRK1B Inhibitor

JH-XVII-10 is a highly selective inhibitor of DYRK1A and DYRK1B, exhibiting IC50 values of 3 nM and 5 nM, respectively. This compound demonstrates significant antitumor activity in head and neck squamous cell carcinoma (HNSCC) cell lines. JH-XVII-10 is suitable for research applications focusing on dysregulation of DYRK kinases in cancer.

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JH-XVII-10 3034312-17-6 DYRK1A/DYRK1B Inhibitor

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Biological Activity

Description	JH-XVII-10 is a highly selective inhibitor of DYRK1A and DYRK1B, exhibiting IC50 values of 3 nM and 5 nM, respectively. This compound demonstrates significant antitumor activity in head and neck squamous cell carcinoma (HNSCC) cell lines. JH-XVII-10 is suitable for research applications focusing on dysregulation of DYRK kinases in cancer.

Product Information

Catalog Num	A31914
Formula	C22H18F4N8O
Molecular Weight	486.42
CAS Number	3034312-17-6
SMILES	FC(F)(F)C1=NN2C=C1C3=C(F)NC4=NC=C(C=C43)C5=C(C#N)N(C)N=C5CN(C)C(CCC2)=O

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