Fig. 1 · Structure
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JJH260
AIG1 Inhibitor
JJH260 is an AIG1 inhibitor that selectively inhibits fluorophosphonate reactivity and fatty acid ester hydrolysis activity mediated by AIG1 in HEK293T cells. This compound demonstrates potent inhibitory effects, with IC50 values of 0.50 μM for fluorophosphonate reactivity and 0.57 μM for FAHFA hydrolysis. JJH260 serves as a valuable tool for understanding the biological functions of AIG1 and its role in relevant metabolic pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1831135-30-8 |
| Applications | AIG1 Inhibitor |
| Formula | C29H34ClN5O5 |
| Molecular Weight | 568.06 |
| SMILES | CN(C1=CC=C(C(N2CCN(C3C2)C(N(C3=O)OC(N4CCC(CC4)CCC5=CC=C(C=C5)Cl)=O)=O)=O)C=C1)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.