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JLB2-110c

Melanocortin Agonist

JLB2-110c is a potent melanocortin receptor agonist, specifically targeting the melanocortin-4 receptor (MC4R) with an EC50 of 0.34 nM. This compound demonstrates significant appetite suppressant effects in vivo, making it a valuable tool for research into obesity and metabolic disorders. Its ability to modulate energy homeostasis positions JLB2-110c as a key reagent for studies related to appetite regulation and weight management.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	3032608-72-0
Applications	Melanocortin Agonist
Formula	C₇₁H₁₀₈N₂₈O₁₂
Molecular Weight	1545.80
SMILES	C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CC4=CC=CC=C4)NC(=O)[C@H](CC5=CN=CN5)NC(=O)C6(N(C(=O)[C@@]7(N(C(=O)[C@H](CCCCNC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)NC(C)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)NC(=O)[C@H](CN)NC3=O)CCC7)[H])CCC6)[H]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.