Fig. 1 · Structure
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JM6
Neuroprotective Agent
JM6 is a weak inhibitor of kynurenine 3-monooxygenase (KMO), exhibiting an IC50 of 19.85 μM in mouse models. This compound serves as a neuroprotective agent, making it a valuable tool for research on neurodegenerative disorders, including Alzheimer's disease. Its use may provide insights into the modulation of neuroinflammatory pathways and metabolic processes associated with neuronal health.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1008119-83-2 |
| Applications | Neuroprotective Agent |
| Formula | C23H26N4O6S2 |
| Molecular Weight | 518.61 |
| SMILES | O=S(C1=CC=C(OC)C(OC)=C1)(NC2=NC(C3=CC=CC([N+]([O-])=O)=C3)=C(CN4CCCCC4)S2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.