Fig. 1 · Structure
Documents & Downloads
JNJ 10181457 dihydrochloride
H3 Antagonist
JNJ 10181457 dihydrochloride is a potent, selective non-imidazole antagonist of the H3 receptor. It has demonstrated the ability to increase norepinephrine and acetylcholine levels in the rat frontal cortex, highlighting its potential in the modulation of neurotransmitter systems. This compound is applicable in neurological research, offering insights into cognitive function and neuropharmacology.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 544707-20-2 |
| Applications | H3 Antagonist |
| Formula | C20H30Cl2N2O |
| Molecular Weight | 385.37 |
| SMILES | N1(CCCCC1)CCC#CC2=CC=CC(CN3CCOCC3)=C2.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.