JNJ-18038683 free base is a potent antagonist of the 5-Hydroxytryptamine Type 7 (5-HT7) receptor, demonstrating pKis of 8.19 and 8.20 for rat and human 5-HT7 receptors, respectively, in HEK293 cell assays. This compound exhibits significant biological activity relevant for the investigation of psychiatric disorders and neuropharmacology. It serves as a valuable tool for researchers exploring the therapeutic potential of 5-HT7 receptor modulation.
JNJ-18038683 free base is a potent antagonist of the 5-Hydroxytryptamine Type 7 (5-HT7) receptor, demonstrating pKis of 8.19 and 8.20 for rat and human 5-HT7 receptors, respectively, in HEK293 cell assays. This compound exhibits significant biological activity relevant for the investigation of psychiatric disorders and neuropharmacology. It serves as a valuable tool for researchers exploring the therapeutic potential of 5-HT7 receptor modulation.
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