JNJ-38877618

Catalog No.: A18325

c-Met inhibitor

JNJ-38877618

JNJ-38877618 Chemical Structure

CAS NO. 943540-74-7

JNJ-38877618 is a novel potent, highly selective, orally bioavailable c-Met tyrosine kinase inhibitor with Kd of 1.2, 2.1 and 21 nM for WT, M1250T and Y1235D mutants MET, respectively.

Availability: In stock

Package Price Qty
5 mg
$200.00
10 mg
$300.00
50 mg
$800.00
100 mg
$1,200.00
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Biological Activity

JNJ-38877618 is a novel potent, highly selective, orally bioavailable c-Met tyrosine kinase inhibitor with Kd of 1.2, 2.1 and 21 nM for WT, M1250T and Y1235D mutants MET, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.71 mL 133.56 mL 267.13 mL
0.5 mM 5.34 mL 26.71 mL 53.43 mL
1 mM 2.67 mL 13.36 mL 26.71 mL
5 mM 0.53 mL 2.67 mL 5.34 mL

*The above data is based on the productmolecular weight 374.355. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18325
Actions Inhibitor
M. Wt 374.355
Formula C20H12F2N6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 943540-74-7
Synonyms JNJ38877618, JNJ 38877618
SMILES FC(C1=CC=C2N=CC=CC2=C1)(F)C3=NN=C4C=CC(C5=CC=NC=C5)=NN43

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