Fig. 1 · Structure
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JNJ-40068782
mGlu2 Receptor Modulator
JNJ-40068782 is a potent positive allosteric modulator of the metabotropic glutamate receptor 2 (mGlu2). With an IC50 value of 38 nM, this compound enhances mGlu2 receptor activity, influencing various neurobiological processes. It is primarily utilized in research investigating neurological disorders and psychiatric conditions, providing insight into mGlu2 signaling pathways and potential therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 950196-50-6 |
| Applications | mGlu2 Receptor Modulator |
| Formula | C21H23N3O |
| Molecular Weight | 333.43 |
| SMILES | N#CC1=C(C=CN(C1=O)CC2CC2)N3CCC(CC3)C4=CC=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.