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| Description | JNJ-64619178 is a PRMT5 inhibitor with high selectivity and potency (subnanomolar range, PRMT5-MEP-50 IC50=0.14 nM) under different in vitro and cellular conditions, paired with favorable pharmacokinetics and safety properties. | |||||
|---|---|---|---|---|---|---|
| Cell Research |
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| Catalog Num | A16861 |
|---|---|
| Formula | C22H23BrN6O2 |
| Molecular Weight | 483.37 |
| CAS Number | 2086772-26-9 |
| SMILES | BrC1=C(N)N=C(C=C(CC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C(N=CN=C4N)=C4C=C3)C2)C=C5)C5=C1 |
| Synonyms | JNJ64619178, JNJ 64619178 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 94 mg/mL (194.47 mM) | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.69 mL | 103.44 mL | 206.88 mL |
| 0.5 mM | 4.14 mL | 20.69 mL | 41.38 mL |
| 1 mM | 2.07 mL | 10.34 mL | 20.69 mL |
| 5 mM | 0.41 mL | 2.07 mL | 4.14 mL |
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
