Fig. 1 · Structure
Documents & Downloads
JNJ-DGAT1-A
DGAT1 Inhibitor
JNJ-DGAT1-A is a selective inhibitor of diacylglycerol acyltransferase 1 (DGAT1), which plays a critical role in triglyceride (TG) synthesis. By inhibiting DGAT1 activity, JNJ-DGAT1-A reduces the accumulation of triglycerides, making it a valuable tool for research into lipid metabolism and related disorders. This compound is utilized in studies aimed at understanding obesity, diabetes, and other metabolic diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1092067-85-0 |
| Applications | DGAT1 Inhibitor |
| Formula | C31H35Cl2N5O3 |
| Molecular Weight | 596.55 |
| SMILES | O=C(N1CCN(C2=CC=C(NC(CC3=CC=C(OC)C=C3)=O)C=C2)CC1)NC4=C(Cl)C=C(CN5CCCC5)C=C4Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.