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Histamine Antagonist

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Catalog No. A12713

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
JNJ7777120 10mg A12713-10

Regular Price: €80.75

Special Price: €72.68

JNJ7777120 25mg A12713-25

Regular Price: €171.00

Special Price: €153.90

JNJ7777120 50mg A12713-50

Regular Price: €285.00

Special Price: €256.50

JNJ7777120 100mg A12713-100

Regular Price: €475.00

Special Price: €427.50

JNJ7777120 10mM * 1mL in DMSO A12713-10mM-D

Regular Price: €78.85

Special Price: €70.97

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

JNJ7777120 is a potent, selective non-imidazole human histamine H4 receptor antagonist.


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Publications citing Adooq Products
JNJ7777120 Citations (2)
  • K Yamamoto, .et al. Activation of orexinergic and histaminergic pathway involved in therapeutic effect of histamine H4 receptor antagonist against cisplatin-induced anorexia in mice, Naunyn-Schmiedeberg's Arch Pharmacol, 2019, pp 1-12
  • Yamamoto K, .et al. Effects of a histamine H4 receptor antagonist on cisplatin-induced anorexia in mice, Neurosci Lett, 2018, May 29;676:103-107 PMID: 29655943

Chemical Information

Catalog Num A12713
Actions Antagonist
M. Wt 277.75
Formula C14H16N3OCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 459168-41-3
Synonyms JNJ 7777120, JNJ-7777120

Biological Activity

JNJ7777120 is a potent, selective non-imidazole human histamine H4 receptor antagonist.


Solubility (25°C) * In vitro DMSO 56 mg/mL (201.62 mM)
Water <1 mg/mL (<1 mM)
Ethanol 8 mg/mL (28.8 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36 mL 180.02 mL 360.04mL
0.5 mM 7.2 mL 36 mL 72.01 mL
1 mM 3.6 mL 18 mL 36 mL
5 mM 0.72 mL 3.6 mL 7.2 mL

*The above data is based on the productmolecular weight 277.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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