JNJ7777120

Catalog No.: A12713

Histamine Antagonist

JNJ7777120

JNJ7777120 Chemical Structure

CAS NO. 459168-41-3

JNJ7777120 is a potent, selective non-imidazole H4?histamine receptor antagonist.

Availability: In stock

Package Price Qty
10 mg
$85.00
25 mg
$180.00
50 mg
$300.00
100 mg
$500.00
10mM * 1mL in DMSO
$83.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • K Yamamoto, .et al. Activation of orexinergic and histaminergic pathway involved in therapeutic effect of histamine H4 receptor antagonist against cisplatin-induced anorexia in mice, Naunyn-Schmiedeberg's Arch Pharmacol, 2019, pp 1-12
  • Yamamoto K, .et al. Effects of a histamine H4 receptor antagonist on cisplatin-induced anorexia in mice, Neurosci Lett, 2018, May 29;676:103-107 PMID: 29655943

Biological Activity

JNJ7777120 is a potent, selective non-imidazole H4?histamine receptor antagonist.
In vitro (25°C) DMSO 56 mg/mL (201.62 mM)
Water <1 mg/mL (<1 mM)
Ethanol 8 mg/mL (28.8 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36 mL 180.02 mL 360.04 mL
0.5 mM 7.2 mL 36 mL 72.01 mL
1 mM 3.6 mL 18 mL 36 mL
5 mM 0.72 mL 3.6 mL 7.2 mL

*The above data is based on the productmolecular weight 277.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12713
Actions Antagonist
M. Wt 277.75
Formula C14H16N3OCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 459168-41-3
Synonyms JNJ 7777120, JNJ-7777120
SMILES CN1CCN(CC1)C(=O)C2=CC3=C(N2)C=CC(=C3)Cl

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy JNJ7777120 | JNJ7777120 Supplier | purchase | cost | manufacturer | order | distributor | buy 459168-41-3| 459168-41-3 Supplier | purchase 459168-41-3 | 459168-41-3 cost | 459168-41-3 manufacturer | order 459168-41-3 | 459168-41-3 distributor
Rewards