Catalog No.: A12713

Histamine Antagonist


JNJ7777120 Chemical Structure

CAS NO. 459168-41-3

JNJ7777120 is a potent, selective non-imidazole H4?histamine receptor antagonist.

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10 mg

Regular Price: $85.00

Special Price $68.00

25 mg

Regular Price: $180.00

Special Price $144.00

50 mg

Regular Price: $300.00

Special Price $240.00

100 mg

Regular Price: $500.00

Special Price $400.00

10mM * 1mL in DMSO

Regular Price: $83.00

Special Price $66.40

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • K Yamamoto, .et al. Activation of orexinergic and histaminergic pathway involved in therapeutic effect of histamine H4 receptor antagonist against cisplatin-induced anorexia in mice, Naunyn-Schmiedeberg's Arch Pharmacol, 2019, pp 1-12
  • Yamamoto K, .et al. Effects of a histamine H4 receptor antagonist on cisplatin-induced anorexia in mice, Neurosci Lett, 2018, May 29;676:103-107 PMID: 29655943

Biological Activity

JNJ7777120 is a potent, selective non-imidazole H4?histamine receptor antagonist.
In vitro (25°C) DMSO 49 mg/mL (176.42 mM)
Water Insoluble
Ethanol 7 mg/mL (25.2 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 19 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36 mL 180.02 mL 360.04 mL
0.5 mM 7.2 mL 36 mL 72.01 mL
1 mM 3.6 mL 18 mL 36 mL
5 mM 0.72 mL 3.6 mL 7.2 mL

*The above data is based on the productmolecular weight 277.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12713
Actions Antagonist
CAS No. 459168-41-3
Formula C14H16N3OCl
M. Wt 277.75
Purity >98%
Synonyms JNJ 7777120, JNJ-7777120

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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