Fig. 1 · Structure
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JP1302
α2C-Adrenoceptor Antagonist
JP1302 is a highly selective antagonist of the α2C-adrenoceptor, exhibiting a Kb of 16 nM and a Ki of 28 nM for the human α2C receptor. This compound demonstrates significant antidepressant and antipsychotic-like effects, making it a valuable tool for studying neuropsychiatric disorders. Additionally, JP1302 may have applications in research related to renal dysfunction.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 80259-18-3 |
| Applications | α2C-Adrenoceptor Antagonist |
| Formula | C24H24N4 |
| Molecular Weight | 368.47 |
| SMILES | CN1CCN(C2=CC=C(NC3=C(C=CC=C4)C4=NC5=CC=CC=C53)C=C2)CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.