Fig. 1 · Structure
Documents & Downloads
JQ-1-Azidopropylamine
Target Protein Ligand-Linker Conjugate
JQ-1-Azidopropylamine is a target protein ligand-linker conjugate that features a BRD4 ligand and a PROTAC linker designed to recruit E3 ligases. This compound serves as a critical component for the synthesis of the PROTAC JY-21. It facilitates targeted protein degradation, allowing for in-depth studies in cellular signaling and therapeutic interventions in oncology research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2915642-70-3 |
| Applications | Target Protein Ligand-Linker Conjugate |
| Formula | C22H23ClN8OS |
| Molecular Weight | 482.99 |
| SMILES | CC1=NN=C2[C@@H](N=C(C3=C(N12)SC(C)=C3C)C4=CC=C(C=C4)Cl)CC(NCCCN=[N+]=[N-])=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.