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Biological Activity
JQEZ5 is a potent and selective SAM-competitive EZH2 lysine methyltransferase inhibitor with IC50 value of 11 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.43 mL | 92.14 mL | 184.27 mL |
| 0.5 mM | 3.69 mL | 18.43 mL | 36.85 mL |
| 1 mM | 1.84 mL | 9.21 mL | 18.43 mL |
| 5 mM | 0.37 mL | 1.84 mL | 3.69 mL |
*The above data is based on the productmolecular weight 542.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16961 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1913252-04-6 |
| Formula | C30H38N8O2 |
| M. Wt | 542.68 |
| Purity | >98% |
| Synonyms | JQEZ-5, JQEZ 5, JQ-EZ-05, JQ-EZ05, JQ-EZ 05 |
| SMILES | CC(C)N1N=CC2=C(C=C(N=C12)C3=CC=C(N4CCN(CC4)C)N=C3)C(NCC5=C(CCC)C=C(C)NC5=O)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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