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JT71

MrkH Inhibitor

JT71 is a selective inhibitor of the transcriptional activator MrkH, targeting biofilm formation in Klebsiella pneumoniae. By reducing the activity of the mrkA promoter, JT71 effectively disrupts biofilm development without compromising cell viability. This reagent is suitable for research focused on understanding and managing Klebsiella pneumoniae infections and associated biofilm-related complications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	380887-90-1
Applications	MrkH Inhibitor
Formula	C₁₈H₁₈N₂O₂S
Molecular Weight	326.41
SMILES	O=C(NC1=C(C#N)C(CCCCC2)=C2S1)C3=CC=CC=C3OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.