JTP-117968

Catalog No.: A64784
Glucocorticoid Receptor Modulator
JTP-117968 is a selective glucocorticoid receptor modulator that acts as a non-steroidal SGRM with an IC50 of 6.8 nM. This compound demonstrates enhanced transrepression/transactivation dissociation, making it a valuable tool for studying glucocorticoid signaling pathways. Its unique pharmacological profile supports research in inflammation, autoimmune diseases, and other conditions where modulation of glucocorticoid activity may be beneficial.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionJTP-117968 is a selective glucocorticoid receptor modulator that acts as a non-steroidal SGRM with an IC50 of 6.8 nM. This compound demonstrates enhanced transrepression/transactivation dissociation, making it a valuable tool for studying glucocorticoid signaling pathways. Its unique pharmacological profile supports research in inflammation, autoimmune diseases, and other conditions where modulation of glucocorticoid activity may be beneficial.
Product Information
Catalog NumA64784
FormulaC31H31F3N2O2
Molecular Weight520.59
CAS Number2250132-99-9
SMILESO=C(C(C=C1C2)=CC=C1[C@]3(CC4=CC=CC=C4)CC[C@@](C(F)(F)F)(O)C[C@@]3([H])C52CC5)NC6=CC=CN=C6C
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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