Fig. 1 · Structure
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JTP-70902
p15INK4b Inducer
JTP-70902 is a potent inducer of p15INK4b, functioning as a MEK1/2 inhibitor. This compound demonstrates significant antitumor activity, making it a valuable tool in cancer research. It is particularly useful for studies focused on cell cycle regulation and the exploration of therapeutic strategies targeting the MAPK pathway.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inducer |
| CAS Number | 871696-49-0 |
| Applications | p15INK4b Inducer |
| Formula | C24H21BrFN5O5S |
| Molecular Weight | 590.42 |
| SMILES | CS(=O)(NC1=CC=CC(N(C2=O)C3=C(C(N2C4CC4)=O)C(NC5=CC=C(C=C5F)Br)=CC(N3C)=O)=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.