Fig. 1 · Structure

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JWU-A021

GLP-1 Secretagogue

JWU-A021 is a GLP-1 secretagogue that functions by activating the TRPA1 cation channel, resulting in a calcium ion influx and increased intracellular calcium levels in enteroendocrine cells and TRPA1-transfected cells. This activation subsequently stimulates the secretion of glucagon-like peptide-1 (GLP-1) from intestinal enteroendocrine and L cells. JWU-A021 is valuable for research in the context of type 2 diabetes, offering insights into GLP-1 modulation and its potential therapeutic implications.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1403610-23-0
Applications GLP-1 Secretagogue
Formula C16H16ClN
Molecular Weight 257.76
SMILES
ClC1=CC2=C(NC3=C2C(C)(C4C=CC3C4)C)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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