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κ-Bungarotoxin

α3β2 Receptor Antagonist

κ-Bungarotoxin is a potent and selective antagonist of the α3β2 neuronal nicotinic acetylcholine receptors, featuring a slow reversible binding mechanism with an IC50 of 2.30 nM. Its primary biological activity involves blocking neurotransmission at these receptors, making it a valuable tool in studies of synaptic transmission and neuropharmacology. Research applications include the investigation of nicotine addiction, pain modulation, and neurodegenerative diseases where α3β2 receptors play a critical role.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	124511-67-7
Applications	α3β2 Receptor Antagonist
Formula	C₃₀₃H₄₇₅N₉₁O₉₇S₁₀
Molecular Weight	7265.22
Synonyms	κ-Bgt

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.