K-Ras G12C-IN-1

Catalog No.: A20937

K-ras G12C inhibitor

K-Ras G12C-IN-1

K-Ras G12C-IN-1 Chemical Structure

CAS NO. 1629265-17-3

K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C extracted from patent WO 2014152588 A1.

Availability: In stock

Package Price Qty
1 mg
$162.00
5 mg
$486.00
10 mg
$828.00
50 mg
$2,484.00
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Biological Activity

K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C extracted from patent WO 2014152588 A1.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.3 mL 111.52 mL 223.05 mL
0.5 mM 4.46 mL 22.3 mL 44.61 mL
1 mM 2.23 mL 11.15 mL 22.3 mL
5 mM 0.45 mL 2.23 mL 4.46 mL

*The above data is based on the productmolecular weight 448.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20937
Actions Inhibitor
CAS No. 1629265-17-3
Formula C22H23Cl2N3O3
M. Wt 448.34
Solubility DMSO
Purity >98%
SMILES ClC(C=C(OC)C(NCC(N1CCN(C(C=C)=O)CC1)=O)=C2)=C2C3=CC=CC=C3Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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