Fig. 1 · Structure
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K-Ras G12C-IN-4
Ras Inhibitor
K-Ras G12C-IN-4 is a potent covalent inhibitor targeting the KRAS G12C mutation. This compound effectively disrupts the oncogenic signaling pathways associated with mutant KRAS, making it a valuable tool in cancer research. Its application extends to studying therapeutic approaches for tumors harboring KRAS G12C mutations, providing insights into potential treatment strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2376328-55-9 |
| Applications | Ras Inhibitor |
| Formula | C31H33ClN4O4 |
| Molecular Weight | 561.07 |
| SMILES | O=C(NC1CN(C(C=C)=O)C1)CN2C(C3CC3)=C(C(N4CC5=C(C(OC)=CC=C5)CC4)=O)C6=C2C(C)=CC(Cl)=C6 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.