Fig. 1 · Structure
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K-TMZ
Antitumor Agent
K-TMZ is an antitumor agent that targets O6-methylguanine DNA methyltransferase (MGMT) deficient cells. It demonstrates significant efficacy in combating glioblastoma, making it a valuable tool for cancer research. Its use can facilitate studies aimed at understanding the mechanistic pathways of tumor resistance and sensitivity, aiding in the development of targeted therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2269482-26-8 |
| Applications | Antitumor Agent |
| Formula | C7H7N5O2 |
| Molecular Weight | 193.16 |
| SMILES | O=C(N(C)N=N1)N2C1=C(C(C)=O)N=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.