Kaempferol-7-O-rhamnoside is a potent inhibitor of the PD-1/PD-L1 pathway and an agonist of the farnesoid X receptor (FXR). It exhibits cardioprotective properties by targeting the AMPKα1 signaling pathway, significantly enhancing mRNA expression of AMPKα1 in H9c2 cardiomyocytes. Additionally, Kaempferol-7-O-rhamnoside effectively reverses acetaminophen-induced reductions in glutathione levels and mitigates reactive oxygen species production in L02 cells. This compound demonstrates potential applications in research related to heart failure and oxidative stress.
Kaempferol-7-O-rhamnoside is a potent inhibitor of the PD-1/PD-L1 pathway and an agonist of the farnesoid X receptor (FXR). It exhibits cardioprotective properties by targeting the AMPKα1 signaling pathway, significantly enhancing mRNA expression of AMPKα1 in H9c2 cardiomyocytes. Additionally, Kaempferol-7-O-rhamnoside effectively reverses acetaminophen-induced reductions in glutathione levels and mitigates reactive oxygen species production in L02 cells. This compound demonstrates potential applications in research related to heart failure and oxidative stress.
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