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KAT6-IN-4

KAT6 Inhibitor

KAT6-IN-4 is a selective inhibitor of lysine acetyltransferase 6 (KAT6), effectively suppressing the transcription of oncogenes such as ERα. This compound exhibits significant antitumor efficacy in ER+/HER2- breast cancer xenografts, making it a valuable tool for research into KAT6-driven malignancies, including breast cancer and non-small cell lung cancer (NSCLC). KAT6-IN-4 serves as a critical reagent for investigating the role of acetylation in cancer progression and potential therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2901797-38-2
Applications	KAT6 Inhibitor
Formula	C₂₂H₂₂N₄O₆S
Molecular Weight	470.50
SMILES	O=S(NC1=NOC2=CC(CN3N=CC=C3)=C4C(OCCC4)=C21)(C5=C(OC)C=CC=C5OC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.