Fig. 1 · Structure

Documents & Downloads

kb NB 142-70

Cat. No. A12423 CAS 1233533-04-4

PKD inhibitor

kb NB 142-70 is a selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively).

In Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Biological Activity

Target & Activity

Target Activity Value
PKD1 IC50 28.3 nM
PKD3 IC50 53.2 nM
PKD2 IC50 58.7 nM

Cellular Effect

Cell Line Activity Value Description Reference
LNCaP IC50 2.2 μM Inhibition of PKD1 autophosphorylation at Ser916 in human PMA-induced LNCAP cells by Western blotting [PMID: 21617763]

Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1233533-04-4
Applications PKD inhibitor
Formula C11H9NO2S2
Molecular Weight 251.32
SMILES
C1CSC2=C(C(=O)N1)SC3=C2C=C(C=C3)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Added to your cart

View Cart Checkout
Loading...