KB02-COOH

Catalog No.: A80480
Ligands for E3 Ligase
KB02-COOH is a chemical compound that serves as a ligand for E3 ligase, playing a crucial role in the ubiquitin-proteasome system. This fragment is essential for the synthesis of proteolysis-targeting chimeras (PROTACs), including variants such as KB02-JQ1 and KB02-SLF. Researchers can utilize KB02-COOH in studies focused on targeted protein degradation and the modulation of protein activity within cellular pathways.
Grouped product items
Size Price Stock Qty
5mg
$55.00
In stock
10mg
$95.00
In stock
25mg
$200.00
In stock
50mg
$345.00
In stock
100mg
$585.00
In stock
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKB02-COOH is a chemical compound that serves as a ligand for E3 ligase, playing a crucial role in the ubiquitin-proteasome system. This fragment is essential for the synthesis of proteolysis-targeting chimeras (PROTACs), including variants such as KB02-JQ1 and KB02-SLF. Researchers can utilize KB02-COOH in studies focused on targeted protein degradation and the modulation of protein activity within cellular pathways.
Product Information
Catalog NumA80480
FormulaC13H14ClNO4
Molecular Weight283.71
CAS Number2375196-30-6
SMILESO=C(O)COC1=CC2=C(N(C(CCl)=O)CCC2)C=C1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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