Documents & Downloads

KB03-SLF

Nucleoprotein PROTAC Degrader

KB03-SLF is an electrophilic PROTAC degrader targeting DCAF16 to facilitate the degradation of the nuclear protein FKBP12. This compound serves as a valuable tool in cancer research, enabling the investigation of protein homeostasis and degradation pathways. KB03-SLF’s unique structure incorporates specific ligands that enhance its efficacy as a degradative agent, making it a significant asset for studies focused on targeted protein elimination.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	2384184-42-1
Applications	Nucleoprotein PROTAC Degrader
Formula	C₅₀H₆₃ClF₃N₅O₁₂
Molecular Weight	1018.51
SMILES	O=C([C@H]1N(CCCC1)C(C(C(C)(C)CC)=O)=O)O[C@@H](C2=CC(NC(CCOCCOCCNC(CCNC(C3=CC(NC(CCl)=O)=CC(C(F)(F)F)=C3)=O)=O)=O)=CC=C2)CCC4=CC(OC)=C(C=C4)OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.