Fig. 1 · Structure
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KCC2 blocker 1
KCC2 Blocker
KCC2 Blocker 1 is a selective inhibitor of the K+-Cl- cotransporter KCC2, exhibiting an IC50 value of 1 μM. This compound, classified as a benzyl prolinate, has been utilized in research to investigate the functional roles of KCC2 in cellular processes and neuronal signaling. Its ability to modulate ion transport mechanisms makes it a valuable tool for studying pathophysiological conditions associated with KCC2 dysregulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1228439-36-8 |
| Applications | KCC2 Blocker |
| Formula | C22H25NO5S |
| Molecular Weight | 415.50 |
| SMILES | O=C(OCC1=CC=CC=C1)C2(CC3=CC=C(S(=O)(C)=O)C=C3)N(C(C)=O)CCC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.