Fig. 1 · Structure
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KCC2 Modulator-3
KCC2 Modulator
KCC2 Modulator-3 is a potent modulator of the KCC2 transporter, exhibiting an EC50 of 0.253 μM. This compound is valuable for research into neurological disorders, including epilepsy, neuropathic pain, and Rett syndrome. Its ability to influence chloride ion transport makes it a crucial tool for studying synaptic transmission and neuronal excitability.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 2704531-38-2 |
| Applications | KCC2 Modulator |
| Formula | C35H39N7O3 |
| Molecular Weight | 605.73 |
| SMILES | O=C1C2=C(CN1C(C)C)C(NC3=CC=C(C4=CC=C(OCCC5(CCC#C)N=N5)C=C4)C=C3)=NC(N6CCOC(C7CC7)C6)=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.