Fig. 1 · Structure
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KCNK13-IN-1
KCNK13 Antagonist
KCNK13-IN-1 is a selective antagonist of the KCNK13 ion channel. It exhibits potent anti-inflammatory activity, demonstrated by an IC50 of less than 200 nM for the inhibition of IL-1β. This reagent is valuable for research applications aimed at understanding inflammation mechanisms and exploring therapeutic strategies for inflammatory diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 361368-24-3 |
| Applications | KCNK13 Antagonist |
| Formula | C15H12N6O |
| Molecular Weight | 292.30 |
| SMILES | NC1=NON=C1C2=NC3=CC=CC=C3N2CC4=CC=NC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.