Fig. 1 · Structure
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KCNQ1 activator-1
KCNQ1 Activator
KCNQ1 activator-1 is a potent KCNQ1 channel activator with an EC50 of 1.69 μM. This compound is valuable for investigating the mechanisms underlying long QT syndrome (LQTS). By modulating KCNQ1 activity, KCNQ1 activator-1 facilitates research into cardiac rhythm disorders and their potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1008671-38-2 |
| Applications | KCNQ1 Activator |
| Formula | C22H23N3O4S2 |
| Molecular Weight | 457.57 |
| SMILES | O=C(C1N(S(=O)(C2=CC=CC=C2)=O)CCCC1)NC3=NC(C4=CC=C(OC)C=C4)=CS3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.