Fig. 1 · Structure
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Ketoprofen-d4
Stable Isotope
Ketoprofen-d4 is the deuterated form of Ketoprofen, a non-steroidal anti-inflammatory drug (NSAID) that primarily acts as a potent inhibitor of cyclooxygenase (COX) enzymes. It demonstrates significant inhibitory activity with IC50 values of 2 nM for COX-1 and 26 nM for COX-2 in human blood monocytes. Ketoprofen-d4 is used in chemical research to study the metabolism and pharmacokinetics of Ketoprofen, helping to elucidate its biological effects and therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1219805-29-4 |
| Applications | Stable Isotope |
| Formula | C16H10D4O3 |
| Molecular Weight | 258.31 |
| Synonyms | RP-19583-d4 |
| SMILES | O=C(C1=CC=CC=C1)C2=CC(C(C([2H])([2H])[2H])([2H])C(O)=O)=CC=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.