Fig. 1 · Structure

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KF-17625

Bronchodilator

KF-17625 is an orally active bronchodilator that primarily targets bronchial smooth muscle relaxation. It effectively inhibits bronchoconstriction induced by agents such as Carbachol, Histamine, and Leukotriene D4. Additionally, KF-17625 demonstrates inhibition of canine tracheal phosphodiesterase IV with an IC50 of 12 μM and reduces Concanavalin-A-induced histamine release from rat mast cells by 44% at 10 mM. This compound is valuable for research in immunology and inflammation.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 139339-02-9
Applications Bronchodilator
Formula C15H10N4O
Molecular Weight 262.27
SMILES
O=C1C2=C(C3=C(N1C4=CC=CC=C4)N=CC=C3)NC=N2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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