Fig. 1 · Structure

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KF 22678

Anti-cancer Agent

KF 22678 is a thioester derivative of leinamycin that acts as an anti-cancer agent. It demonstrates a broad antitumor spectrum, effectively targeting various human carcinoma xenografts, including lung, colon, ovarian, and prostate cancers. This compound serves as a valuable tool for cancer research, aiding in the exploration of therapeutic strategies against multiple cancer types.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 186643-40-3
Applications Anti-cancer Agent
Formula C32H38N2O10S3
Molecular Weight 706.85
SMILES
CC1=C(OC(O1)=O)CSC([C@](O)([C@@]2(C3)S(N([C@@H](C4=NC(/C=C\C=C\C([C@H](O[C@]5([H])CCCCO5)/C=C(C)\CC2)=O)=CS4)C)C3=O)=O)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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