Ki8751

Catalog No.: A10502

VEGFR-2 inhibitor

Ki8751

Ki8751 Chemical Structure

CAS NO. 228559-41-9

Ki8751 is a cell-permeable quinolyloxyphenyl-urea compound that acts as a Flk-1 (VEGFR-2)-selective inhibitior in both cell-based and cell-free assays.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $50.00

Special Price $40.00

10 mg

Regular Price: $75.00

Special Price $60.00

50 mg

Regular Price: $300.00

Special Price $240.00

100 mg

Regular Price: $500.00

Special Price $400.00

10mM * 1mL in DMSO
$80.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

Ki8751 is a cell-permeable quinolyloxyphenyl-urea compound that acts as a Flk-1 (VEGFR-2)-selective inhibitior in both cell-based and cell-free assays.
Targets
Target Value
VEGFR2IC50: 0.9nM
c-KitIC50: 40nM
PDGFRαIC50: 67nM
FGFR2IC50: 170nM
EGFRIC50: >10μM
HGFRIC50: >10μM
Insulin ReceptorIC50: >10μM
In vitro DMSO 47 mg/mL (100.12 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.3 mL 106.52 mL 213.04 mL
0.5 mM 4.26 mL 21.3 mL 42.61 mL
1 mM 2.13 mL 10.65 mL 21.3 mL
5 mM 0.43 mL 2.13 mL 4.26 mL

*The above data is based on the productmolecular weight 469.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10502
Actions Inhibitor
M. Wt 469.4
Formula C24H18F3N3O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 228559-41-9
Synonyms Ki-8751
SMILES COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC(=C(C=C3)NC(=O)NC4=C(C=C(C=C4)F)F)F

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