KIF18A-IN-16

Catalog No.: A54771
KIF18A Inhibitor
KIF18A-IN-16 is a potent inhibitor of KIF18A, a kinesin motor protein involved in mitotic spindle assembly and chromosome segregation. This compound has demonstrated significant biological activity in preclinical models and is valuable for research applications in oncology, particularly in the study of various cancer types, including colon, breast, and lung cancer. Its ability to disrupt KIF18A function makes it a promising candidate for investigating novel therapeutic strategies in cancer treatment.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKIF18A-IN-16 is a potent inhibitor of KIF18A, a kinesin motor protein involved in mitotic spindle assembly and chromosome segregation. This compound has demonstrated significant biological activity in preclinical models and is valuable for research applications in oncology, particularly in the study of various cancer types, including colon, breast, and lung cancer. Its ability to disrupt KIF18A function makes it a promising candidate for investigating novel therapeutic strategies in cancer treatment.
Product Information
Catalog NumA54771
FormulaC30H37N5O4S
Molecular Weight563.71
CAS Number3033981-01-7
SMILESO=C(C1=C(CCC2)C2=C(NS(=O)(CCO)=O)C=C1N3CCC4(CC4)CC3)NC5=CC=CC6=C5N=C7N6CCCC7
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