KIF18A-IN-18

Catalog No.: A54768
KIF18A Inhibitor
KIF18A-IN-18 is a selective inhibitor of KIF18A, a motor protein involved in chromosome segregation during cell division. This compound has demonstrated the ability to disrupt KIF18A’s function, making it a valuable tool for studying chromosomal instability in tumors. Its application extends to research focused on understanding the mechanisms of tumorigenesis and potential therapeutic strategies in the context of cancer.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKIF18A-IN-18 is a selective inhibitor of KIF18A, a motor protein involved in chromosome segregation during cell division. This compound has demonstrated the ability to disrupt KIF18A’s function, making it a valuable tool for studying chromosomal instability in tumors. Its application extends to research focused on understanding the mechanisms of tumorigenesis and potential therapeutic strategies in the context of cancer.
Product Information
Catalog NumA54768
FormulaC29H34F2N4O5S
Molecular Weight588.67
CAS Number3039911-45-7
SMILESOCCS(NC1=CC=C(C(NC2=C(C=C3N4CCC(F)(F)C3)C4=C(OC)C=C2)=O)C(N5CCC6(CC6)CC5)=C1)(=O)=O
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