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Kinase modulator-1

Kinase Modulator

Kinase Modulator-1 is an inhibitor specifically targeting Bcr-Abl kinase activity, including resistant mutants such as T315I. This compound demonstrates significant anti-cancer activity, making it a valuable tool for research in chronic myelogenous leukemia (CML). Its ability to modulate kinase activity offers insights into therapeutic strategies for overcoming drug resistance in related malignancies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	927697-17-4
Applications	Kinase Modulator
Formula	C₂₅H₂₄N₄O₄
Molecular Weight	444.48
SMILES	O=C(NC1=C(C(N(C)C)=O)C=C(C2=CN=C3NC=C(C3=C2)C4=C(OC)C=CC=C4)C=C1)OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.