KIO-301 is a photoswitchable blocker of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. This compound serves as a versatile tool for research in retinal diseases, specifically targeting the reactivation of HCN channels in models of retinitis pigmentosa. Its ability to be controlled by light makes it particularly useful for studies requiring precise spatiotemporal modulation of channel activity.
KIO-301 is a photoswitchable blocker of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. This compound serves as a versatile tool for research in retinal diseases, specifically targeting the reactivation of HCN channels in models of retinitis pigmentosa. Its ability to be controlled by light makes it particularly useful for studies requiring precise spatiotemporal modulation of channel activity.
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