Kira8 Hydrochloride

Catalog No.: A21780
IRE1α inhibitor
Kira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
Grouped product items
Product Name Price Stock Qty
Kira8 Hydrochloride 1mg
$320.00
In stock
Kira8 Hydrochloride 5mg
$960.00
In stock
Kira8 Hydrochloride 10mg
$1,600.00
In stock
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Biological Activity
Discription Kira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
Product Information
Catalog Num A21780
Formula C31H30Cl2N6O3S
Molecular Weight 637.58
CAS Number 2250019-92-0
SMILES O=S(C1=CC=CC=C1Cl)(NC2=C3C=CC(C)=C(C3=CC=C2)OC4=NC=CC=C4C5=NC(N[C@H]6CNCCC6)=NC=C5)=O.[H]Cl
Synonyms AMG-18 Hydrochloride, AMG18, AMG 18; Kira-8, Kira 8
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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