Fig. 1 · Structure
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Kirromycin
EF-Tu Inhibitor
Kirromycin is an elongation factor Tu (EF-Tu) inhibitor that disrupts protein biosynthesis in bacterial cells. This antibiotic exhibits antibacterial activity against Gram-negative bacteria by targeting EF-Tu and interfering with the peptidyl transfer reaction. Kirromycin is valuable for research applications focused on bacterial infections and can aid in understanding the mechanisms of antibiotic resistance and protein synthesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 50935-71-2 |
| Applications | EF-Tu Inhibitor |
| Formula | C43H60N2O12 |
| Molecular Weight | 796.94 |
| Synonyms | Mocimycin; Delvomycin |
| SMILES | O=C(NC/C=C/C=C(C)/[C@@H](OC)[C@H]([C@]([C@H]([C@H]1O)O)([H])O[C@@H]1/C=C/C=C/C=C(C)/C(C(C2=O)=C(C=CN2)O)=O)C)[C@H]([C@@](O[C@H](C(C)3C)/C=C/C=C\C)([C@@H]([C@@H]3O)O)O)CC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.